Cathepsin S is a protein that in humans is encoded by the CTSS gene. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Cathepsin S is a member of the peptidase C1 family and is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation to the MHC class II. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages.

Gene: Ctss ENSMUSG00000038642 Gene Synonyms. Cat S. Location This gene has proteins that correspond to the following Uniprot identifiers: P30279.

An important paralog of this gene is CTSF. MGI:107341, Ctss Gene expression databases. Bgee i: ENSMUSG00000038642, Expressed in camera-type eye and 295 other tissues: Genevisible i: O70370, MM: CTSS. 117: Annotation score: Experimental Info. Feature key Gene expression databases. Bgee i: ENSG00000163131, Expressed in monocyte and 221 other tissues: This gene is known to be important for immune responses and may potentially regulate alcohol consumption. Cat-S activates nociceptors to induce visceral pain via protease-activated receptor-2.

Ctss gene

GEPIA2 database analysis showed higher CTSS expression in glioblastoma tissues than in normal tissues. Both mRNA and protein levels of CTSS in T98G-R cells were significantly higher than those in T98G cells. CTSS (cathepsin S), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol. Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumors Cancer-Prone Deep Insight Case Reports Journals Portal Teaching Gene: CTSS - ENSCAFG00000012086 - Canis lupus familiaris (dog) General information. Ensembl ID: ENSCAFG00000012086: Name: CTSS: Description PrimePCR™ PreAmp for SYBR® Green Assay: CTSS, Human Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

Cat-S activates nociceptors to induce visceral pain via protease-activated receptor-2.

CTSL, CTSO, CTSS, CTSV, CTSW, CTSZ, CTTN, CTTNBP2, CTTNBP2NL Mutation and Gene Expression (Brueffer et al, 2020), PTEN Gene Expression

Reliability scorei. Overall gene reliability score for the subcellular location (s) of the encoded protein (s). CTSS has 5,430 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 78 datasets. Ctss Gene Detail Summary Symbol.

img. Miry's List 2019 Annual Report by Miry's List - issuu. Gene identification and analysis of transcripts img. Gene identification and analysis of transcripts .

Processing and Apr 10, 2018 Cathepsin S (CTSS) and Sirtuin-1 (SIRT1) played crucial roles in the pathogenesis of chronic obstructive pulmonary disease (COPD). However May 5, 2020 Human FL Biopsy Samples with CTSS Y132 Mutations Have Gene Expression Profiles Linked with Antigen Processing and Chemokine Mar 5, 2021 GeneCards Summary for CTSS Gene. CTSS (Cathepsin S) is a Protein Coding gene. Diseases associated with CTSS include Dacryoadenitis Jan 15, 2021 3.7 CTSS clustering. Transcription start sites are found in the promoter region of a gene and reflect the transcriptional activity of that promoter ( Apr 15, 2015 Produced from its cognate CTSS gene on chromosome 1q21, human cathepsin S is synthesized as a pre-proenzyme of 331 amino acids in Gene symbol, CTSS. Aliases, -. Protein Name, Cathepsin S. Function, Cathepsin S is a member of the peptidase C1 family and is a lysosomal cysteine protease Furthermore, the gene-expression profile of ALD hHSCs was compared with that trix metallopeptidase 9), CD14, CTSS (cathepsin S), TYROBP (TYRO protein May 6, 2016 To examine the functional ramifications associated with greater Ctss expression, the Ctss gene was deleted in the mdx genetic background, May 8, 2018 Hub genes [APOE, cathepsin S (CTSS), insulin receptor substrate 1 (IRS1), Four gene expression profiles, GSE3467, GSE29265, GSE33630 Dec 23, 2020 Cathepsin S (CTSS), a lysosomal cysteine protease, The primer sequences of MT-ND1 gene was used for mtDNA amplification.

Catalog # A15629, A15630 Non-tailed | Desalted | Pair : See in cart, See in cart Add Pair To Cart Add to Array View Description: Homo sapiens cathepsin S (CTSS), transcript variant 1, mRNA. (from RefSeq NM_004079) RefSeq Summary (NM_004079): The preproprotein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that participates in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. . The mature protein cleaves the invariant CTSS (cathepsin S), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol. Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumors Cancer-Prone Deep Insight Case Reports Journals Portal Teaching Gene Name: Homo sapiens cathepsin S (CTSS), transcript variant 1: Database Link: Entrez Gene 1520 Human. Background: CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases.
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[Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis]. Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma. Cathepsin S is a protein that in humans is encoded by the CTSS gene.

Some features of the site may not work correctly. Because this designation had been used for a different gene (see 600550), the official name of the gene identified by Shi et al.
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May 5, 2020 Human FL Biopsy Samples with CTSS Y132 Mutations Have Gene Expression Profiles Linked with Antigen Processing and Chemokine

Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. Ctss Gene Detail Summary Symbol. Ctss Name. cathepsin S. Synonyms.

Imports a "CTSS" file in a GPos object. CTSS. In CAGEr: Analysis of CAGE ( Cap Analysis of Gene Expression) sequencing data for precise mapping of

This acts as an important initial regulatory mechanism following the translation of the protein and during its localization to the lysosome [ 23 ]. CTSC (Cathepsin C) is a Protein Coding gene. Diseases associated with CTSC include Papillon-Lefevre Syndrome and Haim-Munk Syndrome. Among its related pathways are Vesicle-mediated transport and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding and cysteine-type peptidase activity. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

An important paralog of this gene is CTSF. ctss breaks up proteins into small pieces that may be used to degrade parts of a pathogen.